A recent study using a crossmodal matching task showed that the identity of a talker could be recognized even when the auditory and visual stimuli that were being matched were different sentences spoken by the talker. This finding implies that general temporal features of a person's speech are shared across the auditory and visual modalities.

In this close analysis of Immanuel Kant’s aesthetics in his Critique of Judgment, Dr. Julie N. Books, explains why Kant fails to provide a convincing basis for his desired necessity and universality of our aesthetic judgments about beauty. Drawing upon her extensive background in the visual arts, art history, and philosophy, Dr. Books provides a unique discussion of Kant’s supersensible, illuminating how it cannot justify his a priori nature of our aesthetic judgments about beauty. She uses examples from the (...) history of art, including paintings by Michelangelo, Caravaggio, Rubens, and Constable, to support her views. This book will make a significant addition to courses on the philosophy of Kant, aesthetics, philosophy of art, metaphysics, the history of Western philosophy, ethics, psychology, and art history. (shrink)

Introduction -- 1. Transparency -- Introduction -- Photographs and transparency -- Films and transparency -- Criticisms of transparency --2. Illusionism -- Introduction -- Currie's arguments against cognitive illusionism -- Arguments against cognitive illusionism -- Currie's arguments against perceptual illusionism -- Evaluating perceptual illusionism -- 3. Perceptual realism -- Introduction -- Currie's account of perceptual realism -- Problems with resemblance theories -- 4. Summary -- 5. A new theory of the ontology of film -- Introduction -- Films as creative works of (...) art -- Conclusion. (shrink)

Although performance pressure has desirable consequences, there is evidence that it can produce unintended outcomes as employees tend to engage in dysfunctional and unethical behaviors to meet performance goals. Thus, the process through which employees think and behave unethically under performance pressure deserves more research attention. This study goes beyond the stress-appraisal perspective and investigates whether and when performance pressure influences individual work mindsets and behaviors from a moral reasoning perspective. Specifically, we contend that performance pressure is related to employee (...) expediency through moral decoupling. We further hypothesize dialectical thinking and moral identity to be the boundary conditions of the proposed relationships. Analyses of data from a field study in three waves provide support for most of the hypotheses. In particular, we find that moral decoupling accounts for additional variance after we control for the stress-appraisal effect of performance pressure on employee expediency. The study offers several contributions to the literature on performance pressure and unethical behavior. (shrink)

Student–teacher relationships have been examined by many studies. However, an omission still exists, the existing scales are not appropriate for studying STRs in private colleges because of the special character of these schools. This paper presents the development and validation of Private-College Student–Teacher Relationship Scale, the first instrument to evaluate student–teacher relationships in private colleges. The PCSTRS has six dimensions: trust, interaction, intimacy, care, approval, and comfort. In our main study, the validity and reliability of the six-factor PCSTRS model were (...) demonstrated. The result of internal consistency coefficient indicated the high reliability of the scale, and the result of concurrent validity indicated the significant correlational relationships between the PCSTRS with other STR measures. In supplementary study, the PCSTRS was administered to 360 participants to confirm the applicability of PCSTRS and investigate the relation of STRs and students’ traits, performance, and wellbeing, as well as the differences between the private school and the public school in this relation; the analyses revealed that there were significant differences in trust, intimacy, and care between private and public colleges; positive correlations were found between STRs and self-esteem, self-efficacy, academic performance, extracurricular activity involvement, and subjective wellbeing. Present research firstly develops the PCSTRS, examined the reliability and validity, and provides the proposed nomological network among related constructs. (shrink)

Employees perceive illegitimate tasks as inappropriate assignments because such tasks are beyond what they expect to do in any given job position. Extant literature indicates that, in addition to creating psychological strain and reducing well-being, illegitimate task assignments can result in counterproductive work behavior. This study extends the literature by examining whether illegitimate tasks may lead to two specific forms of CWB targeting organizations: destructive voice and time theft. To understand how and when this happens, we investigate the mediating role (...) of moral disengagement and the moderating role of psychological entitlement. Survey results based on 258 supervisor–subordinate dyads in China reveal that illegitimate tasks are positively related to destructive voice and time theft through moral disengagement. Furthermore, psychological entitlement strengthens the positive relationship between illegitimate tasks and moral disengagement and the indirect effect of illegitimate tasks on destructive voice and time theft. Overall, the findings provide insightful theoretical and managerial implications for research related to illegitimate tasks and CWB. (shrink)

_In _Challenging the One Best System_, a team of leading education scholars offers a rich comparative analysis of the set of urban education governance reforms collectively known as the “portfolio management model.”_ They investigate the degree to which this model—a system of schools operating under different types of governance and with different degrees of autonomy—challenges the standard structure of district governance famously characterized by David Tyack as “the one best system.” The authors examine the design and enactment of the portfolio (...) management model in three major cities: New Orleans, Los Angeles, and Denver. They identify the five interlocking mechanisms at the core of the model—planning and oversight, choice, autonomy, human capital, and school supports—and show how these are implemented differently in each city. Using rich qualitative data from extensive interviews, the authors trace the internal tensions and tradeoffs that characterize these systems and highlight the influence of historical and contextual factors as well. Most importantly, they question whether the portfolio management model represents a fundamental restructuring of education governance or more incremental change, and whether it points in the direction of meaningful improvement in school practices. Drawing on a rigorous, multimethod study, _Challenging the One Best System_ represents a significant contribution to our understanding of system-level change in education. (shrink)

Chromatin composition differs across the genome, with distinct compositions characterizing regions associated with different properties and functions. Whereas many histone modifications show local enrichment over genes or regulatory elements, marking can also span large genomic intervals defining broad chromatin domains. Here we highlight structural and functional features of chromatin domains marked by histone modifications, with a particular emphasis on the potential roles of H3K27 methylation domains in the organization and regulation of genome activity in metazoans. Chromatin domains are extended genomic (...) regions defined by the continuous enrichment of a given histone modification. Here, we review recent work highlighting the presence of chromatin domains in multiple species, their structural aspects in the context of chromatin architecture, and their potential role on the regulation of genome activity. (shrink)

Physical and emotional intimacy between humans and robots may become commonplace over the next decades, as technology improves at a rapid rate. This development provides new questions pertaining to how people perceive robots designed for different kinds of intimacy, both as companions and potentially as competitors. We performed an randomized experiment where participants read of either a robot that could only perform sexual acts, or only engage in non-sexual platonic love relationships. The results of the current study show that females (...) have less positive views of robots, and especially of sex robots, compared to men. Contrary to the expectation rooted in evolutionary psychology, females expected to feel more jealousy if their partner got a sex robot, rather than a platonic love robot. The results further suggests that people project their own feelings about robots onto their partner, erroneously expecting their partner to react as they would to the thought of ones’ partner having a robot. (shrink)

Virtue and the Moral Life brings together distinguished philosophers and theologians with younger scholars of consummate promise to produce ten essays that engage both academics and students of ethics. This collection explores the role virtues play in identifying the good life and the good society.

Virtue and the Moral Life brings together distinguished philosophers and theologians with younger scholars of consummate promise to produce ten essays that engage both academics and students of ethics. This collection explores the role virtues play in identifying the good life and the good society.

In 1822, Alexander Berry (1781–1873), a recent free settler in the early colony of New South Wales (N.S.W.), read a paper on the geology of the coast of N.S.W. to the newly formed Philosophical Soc...

The Protein Ontology (PRO; http://proconsortium.org) formally defines protein entities and explicitly represents their major forms and interrelations. Protein entities represented in PRO corresponding to single amino acid chains are categorized by level of specificity into family, gene, sequence and modification metaclasses, and there is a separate metaclass for protein complexes. All metaclasses also have organism-specific derivatives. PRO complements established sequence databases such as UniProtKB, and interoperates with other biomedical and biological ontologies such as the Gene Ontology (GO). PRO relates to (...) UniProtKB in that PRO’s organism-specific classes of proteins encoded by a specific gene correspond to entities documented in UniProtKB entries. PRO relates to the GO in that PRO’s representations of organism-specific protein complexes are subclasses of the organism-agnostic protein complex terms in the GO Cellular Component Ontology. The past few years have seen growth and changes to the PRO, as well as new points of access to the data and new applications of PRO in immunology and proteomics. Here we describe some of these developments. (shrink)

La defense d'un profond humanisme dont les racines puisent dans la Renaissance ainsi que le souci permanent d'une pedagogie exemplaire ont guide Genevieve Giudicelli-Delage durant toute sa carriere. Professeur emerite de l'Universite Paris 1 Pantheon-Sorbonne, ou elle a notamment dirige pendant de nombreuses annees le DEA devenu Master II de droit penal et politique criminelle en Europe, redactrice en chef de la Revue de science criminelle et de droit penal compare pour les editions Dalloz, presidente de l'Association de recherches penales (...) europeennes (ARPE), directrice de l'Ecole du Centre Ouest des avocats a Poitiers, Genevieve Giudicelli-Delage n'a cesse d'oeuvrer pour un depassement des frontieres disciplinaires et geographiques dans l'approche du phenomene criminel, ce dont temoignent en particulier son engagement en faveur du developpement du droit compare et son attachement a repousser les lignes d'horizons juridiques. Son regard sur le droit penal a profondement marque des generations d'etudiants et de doctorants. Par ses recherches individuelles, comme par les recherches collectives qu'elle mene admirablement, elle a egalement contribue au rayonnement doctrinal du droit penal en general, et de certaines de ses disciplines telles que le droit penal des affaires, le droit international penal, le droit penal europeen ou la procedure penale. C'est donc au chercheur comme au pedagogue que nous avons souhaite rendre hommage par ces Melanges regroupant une soixantaine d'auteurs, anciens eleves/collegues/amis, universitaires et/ou praticiens reunis autour du theme Humanisme et justice, que le Professeur Giudicelli-Delage a, par un soin constant, nourri et questionne durant toutes ses annees d'exercice. (shrink)

Au regard de l'analyse de discours, le déclin économique de la France n'existe pas. L'analyse des controverses médiatiques qui ont suivi la parution en 2003 de l'essai de Nicolas Baverez, La France qui tombe, montre en effet que ni l'histoire, ni la statistique, ni la comparaison géographique ne mènent à la conclusion définitive du déclin et qu'autour de celles-ci s'opposent « déclinophiles » et «déclinophobes». L'analyse de discours révèle la multiplicité des histoires ou des récits économiques autour du déclin, relativisant (...) ainsi l'apparente neutralité des discours sur le déclin économique de la France.In view of discourse analysis, the economic decline of France does not exist. The analysis of media controversies that followed the publication in 2003 of trying to Nicolas Baverez, France falls, shows that neither history nor the statistical or geographical comparisons lead to the conclusion of the final decline and that around them oppose "déclinophiles" and "déclinophobes". The discourse analysis reveals the multiple stories or stories about economic decline, thus relativizing the apparent neutrality of discourse on the economic decline of France. (shrink)

Summary The National Curriculum was introduced into British primary schools in 1989 to raise standards of attainment, especially in the basic skills of English and mathematics. Has this expensive innovation succeeded? This paper analyses the mathematics standards of eight cohorts of Year 6 children from five randomly selected primary schools within one Local Education Authority (n=1503) who had all done Mathematics 11 from 1989 to 1996. Examination of the means of the standardised mathematics scores for each cohort reveals no evidence (...) of rising standards in attainment over the eight years. There are fewer over? and underachievers than one would expect with a tendency for compression of scores around the mean. This paper questions the efficacy of the National Curriculum, assessment procedures and the publication of school performance tables in raising standards in mathematics at Key Stage 2. The need for an effective system of monitoring educational standards throughout the UK is reiterated. (shrink)

Nous remercions Julie Perrin de nous avoir autorisé à reproduire cet article. Il a déjà paru dans le n° 3 d'Ambiances. Revue internationale sur l'environnement sensible, l'architecture et l'espace urbain – Animer l'espace public? Entre programmation urbaine et activation citoyenne, en 2017. Résumé : Dans Walk, Hands, Eyes, l'artiste chorégraphique Myriam Lefkowitz propose à un spectateur à la fois une balade urbaine silencieuse, les yeux fermés. Cet article examine la dimension spatiale, - Urbanisme.

Dans cet ouvrage, Philippe Danino part d’un constat qui fut à l’origine de son questionnement : « Jamais, dans son œuvre, on ne voit Spinoza véritablement exposer ce qu’est la philosophie. Cette idée donne lieu, chez lui, à une réflexivité très rare, ne constituant quasiment jamais un objet visé pour lui-même. Aucune véritable définition, en particulier, n’en est livrée ou travaillée » (p. 9). Là où nous pourrions y lire une constante de la pensée spinoziste – il n’y a ainsi (...) pas plus de défin... (shrink)

Public services worldwide have been subject to externally imposed reforms utilizing tools such as financial incentives and performance targets. The adverse impact of such reforms on a public service ethos has been claimed, but rarely demonstrated. Individuals within organizations work beyond their formal contracts of employment, described as Organizational Citizenship Behavior (OCB), to further organizational interests. Given New Public Management reform and the subsequent contextual changes in the way in which public sector organizations are managed and funded, the present study (...) theorizes that OCB directed towards the organization may be ‘crowded-out’. This article tests the relationships between public service ethos and OCB and it presents empirical evidence from a study in England ( n = 433) of the ability of each dimension of this ethos to predict OCB. (shrink)

L'importance de l'analyse psychologique dans ce que l'on pourrait appeler, à la suite de George Briscoe Kerferd, « le mouvement sophistique », n'est pas en soi une découverte. De nombreuses études se sont en effet attachées à en souligner la portée, notamment dans ses rapports avec l'art rhétorique et son application pratique dans le cadre de la πόλις athénienne du Ve siècle où la parole — sous forme d'ἀγών, de débat contradictoire à l'assemblée ou au tribunal — prévalait sur tous (...) les autres instruments de pouvoir, violence et contrainte physique notamment. Dans un monde où « l’art politique, pour l'essentiel, maniement du langage », selon les mots de Jean-Pierre Vernant, analyser les mécanismes du logos, en connaître les règles, permettait de se rendre maître en persuasion, de posséder un instrument privilégié de victoire. Néanmoins, en marge de cet intérêt manifeste pour l'analyse du pouvoir du λόγος dans le corpus sophistique, on ne trouve, de manière assez paradoxale, qu'un nombre très limité de travaux s'attachant à questionner le sens, le statut et, in fine, la légitimité d'une « psychologie » au sens plein du terme. Et pourtant, la question se pose : peut-on parler d'une psychologie sophistique ou faut-il considérer que pour ces penseurs la ψυχή se donnait comme un état de fait dont il suffisait de connaître empiriquement le mécanisme? Y a-t-il quelque chose en-deçà de la psychagogie chez les sophistes? Dans cet article, nous tenterons de montrer qu’il est possible de voir en Alcidamas, disciple de Gorgias et auteur du Sur ceux qui composent des discours par écrit ou Sur les Sophistes, un éloge paradoxal, puisqu’écrit, de l’improvisation, un penseur de la ψυχή et non plus seulement de la potentialité psychagogique du λόγος. En effet, le développement d'une réflexion riche et complexe sur l’organisation logique et syntactique du discours d’une part, et sur l'âme et ses opérateurs d’autre part – réflexion qui conduit Alcidamas à réévaluer les modalités de relation entre l'orateur et son auditoire — permet de mettre en évidence une redéfinition (bien qu'en filigrane) de l'art rhétorique qui, ne pouvant plus dès lors reposer sur une revendication du pouvoir de la persuasion a maxima, devra accorder à la notion de vraisemblance une place centrale. (shrink)

This paper explores how knowledge is exchanged between agricultural advisors and farmers in the context of sustainable farming practices in England. Specifically the paper examines the nature of the knowledge exchange at the encounters between one group of advisors, agronomists, and farmers. The promotion of best management practices, which are central to the implementation of sustainable agricultural policies in England, provide the empirical context for this study. The paper uses the notion of expert and facilitative approaches as a conceptual framework (...) for analyzing knowledge exchange encounters between agronomists and farmers. Data were derived from semi-structured interviews with 31 agronomists and 17 farmers, in the context of three initiatives promoting a range of best management practices including (a) targeted use of nitrogen (N), (b) use of nutrients within manure, and (c) management practices to improve soil structure. The interviews revealed that, although many agronomist–farmer knowledge exchange encounters are characterized by an imbalance of power, distrust, and the divergence of knowledge, other encounters provide a platform for the facilitation of farmer learning in their transition to more sustainable practices. (shrink)

Motivated by disparities in gun violence, sharp increases in gun ownership, and a changing gun policy landscape, we conducted a nationally representative survey of U.S. adults (n=2,778) in 2021 to compare safety-related views of white, Black, and Hispanic gun owners and non-owners. Black gun owners were most aware of homicide disparities and least expecting of personal safety improvements from gun ownership or more permissive gun carrying. Non-owner views differed. Health equity and policy opportunities are discussed.

Dans cet ouvrage, Philippe Danino part d’un constat qui fut à l’origine de son questionnement : « Jamais, dans son œuvre, on ne voit Spinoza véritablement exposer ce qu’est la philosophie. Cette idée donne lieu, chez lui, à une réflexivité très rare, ne constituant quasiment jamais un objet visé pour lui-même. Aucune véritable définition, en particulier, n’en est livrée ou travaillée ». Là où nous pourrions y lire une constante de la pensée spinoziste – il n’y a ainsi pas plus (...) de défin... (shrink)

IntroductionMilitary personnel and Veterans are at increased risk of mental and physical health conditions, which can impact their families. Spouses often perform a vital role in caring for service members and Veterans facing illness or injury, which can lead to caregiver burden. In turn, this may contribute to relationship issues. Research suggests that ensuring that spouses are well supported can alleviate some of these negative effects. The current study examined whether social support received by spouses of newly released Veterans buffers (...) the impact of Veterans’ health on caregiver burden, subsequently impacting spouses’ relationship satisfaction.MethodsData were collected as part of the Canadian Armed Forces Transition and Well-being Survey. The sample included N = 595 spouses of Regular Force Veterans who released in 2016 with at least 2 years of service. We examined Veterans’ mental and physical health and spouses’ caregiver burden, social support, and relationship satisfaction. A moderated mediation model was tested using structural equation modeling.ResultsThere was a significant indirect association between Veterans’ health and spouses’ relationship satisfaction through caregiver burden. Furthermore, social support moderated the association, as evidenced by a weaker association between Veterans’ health and caregiver burden at low levels of social support compared to high levels.ImplicationsFindings suggest additional efforts should be made to ensure sufficient support is provided to spouses, especially when they are caring for a service member or Veteran facing illness or injury, to strengthen their families’ well-being. (shrink)

L'empirisme transcendantal élaboré par Gilles Deleuze n'est pas le fruit du hasard : il résulte de lectures critiques et d'un véritable remaniement de concepts, notamment dans ses monographies des années cinquante et soixante. Or on lit généralement les œuvres de maturité de Deleuze sans trop s'attarder sur ces premiers écrits. De même, la question de la subjectivité dans son œuvre est souvent laissée au second plan, et l'on constate dans la littérature secondaire des opinions diamétralement opposées quant au statut du (...) sujet chez Deleuze. Le présent ouvrage reconstruit la notion deleuzienne de subjectivité à partir des premières monographies que le philosophe a consacrées à Hume, Kant, Nietzsche et Bergson. Il confronte les œuvres de ces auteurs aux monographies de Deleuze, et réarticule les concepts de la période de 'Différence et répétition' (singularités, habitudes, champ transcendantal, etc.) autour des questions sur la genèse et le statut de la subjectivité."--Page 4 of cover. (shrink)

In this substantial and challenging book, O’Hagan gives central place to three of Rousseau’s works—the Discourse of Inequality, the Emile, and the Social Contract—which, he says, “constitute the axes of Rousseau’s idea of formation. The formation of the human race is the axis of the Second Discourse, the formation of the individual that of the Emile, and the formation of the citizen that of the Social Contract”. However, he also draws extensively on other material, particularly Julie, ou la Nouvelle (...) Héloïse, to extend and deepen some of Rousseau’s accounts, particularly of moral and psychological issues. Such selectivity enables O’Hagan to consider in some detail each of his chosen texts, which he does with persistent intensity and rigor, in chapters 2 to 6, devoting three of these chapters to his treatment of the Social Contract. Additionally, he selects certain topics for particular attention, with individual chapters on amour-propre, on Rousseau’s views about men and women, on Rousseau’s treatment of some issues concerning language, and he closes with an extended treatment of Rousseau’s religious ideas and views about the role of religion in society. It is pleasing to see this aspect of Rousseau’s thought, which is seldom considered at length these days, dealt with with such care. Another useful aspect of O’Hagan’s discussion is that he makes available and engages with some of the ideas of leading French critics of Rousseau, which helpfully broadens the horizons of the assessments he makes. (shrink)

In this substantial and challenging book, O’Hagan gives central place to three of Rousseau’s works—the Discourse of Inequality, the Emile, and the Social Contract—which, he says, “constitute the axes of Rousseau’s idea of formation. The formation of the human race is the axis of the Second Discourse, the formation of the individual that of the Emile, and the formation of the citizen that of the Social Contract”. However, he also draws extensively on other material, particularly Julie, ou la Nouvelle (...) Héloïse, to extend and deepen some of Rousseau’s accounts, particularly of moral and psychological issues. Such selectivity enables O’Hagan to consider in some detail each of his chosen texts, which he does with persistent intensity and rigor, in chapters 2 to 6, devoting three of these chapters to his treatment of the Social Contract. Additionally, he selects certain topics for particular attention, with individual chapters on amour-propre, on Rousseau’s views about men and women, on Rousseau’s treatment of some issues concerning language, and he closes with an extended treatment of Rousseau’s religious ideas and views about the role of religion in society. It is pleasing to see this aspect of Rousseau’s thought, which is seldom considered at length these days, dealt with with such care. Another useful aspect of O’Hagan’s discussion is that he makes available and engages with some of the ideas of leading French critics of Rousseau, which helpfully broadens the horizons of the assessments he makes. (shrink)

Background: Family members are often required to act as substitute decision-makers when health care or research participation decisions must be made for an incapacitated relative. Yet most families are unable to accurately predict older adult preferences regarding future health care and willingness to engage in research studies. Discussion and documentation of preferences could improve proxies' abilities to decide for their loved ones. This trial assesses the efficacy of an advance planning intervention in improving the accuracy of substitute decision-making and increasing (...) the frequency of documented preferences for health care and research. It also investigates the financial impact on the healthcare system of improving substitute decision-making.Methods/DesignDyads (n = 240) comprising an older adult and his/her self-selected proxy are randomly allocated to the experimental or control group, after stratification for type of designated proxy and self-report of prior documentation of healthcare preferences. At baseline, clinical and research vignettes are used to elicit older adult preferences and assess the ability of their proxy to predict those preferences. Responses are elicited under four health states, ranging from the subject's current health state to severe dementia. For each state, we estimated the public costs of the healthcare services that would typically be provided to a patient under these scenarios. Experimental dyads are visited at home, twice, by a specially trained facilitator who communicates the dyad-specific results of the concordance assessment, helps older adults convey their wishes to their proxies, and offers assistance in completing a guide entitled My Preferences that we designed specifically for that purpose. In between these meetings, experimental dyads attend a group information session about My Preferences. Control dyads attend three monthly workshops aimed at promoting healthy behaviors. Concordance assessments are repeated at the end of the intervention and 6 months later to assess improvement in predictive accuracy and cost savings, if any. Copies of completed guides are made at the time of these assessments.DiscussionThis study will determine whether the tested intervention guides proxies in making decisions that concur with those of older adults, motivates the latter to record their wishes in writing, and yields savings for the healthcare system.Trial RegistrationISRCTN89993391. (shrink)

Background If trials of therapeutic interventions are to serve society's interests, they must be of high methodological quality and must satisfy moral commitments to human subjects. The authors set out to develop a clinical - trials compendium in which standards for the ethical treatment of human subjects are integrated with standards for research methods. Methods The authors rank-ordered the world's nations and chose the 31 with >700 active trials as of 24 July 2008. Governmental and other authoritative entities of the (...) 31 countries were searched, and 1004 English-language documents containing ethical and/or methodological standards for clinical trials were identified. The authors extracted standards from 144 of those: 50 designated as ‘core’, 39 addressing trials of invasive procedures and a 5% sample of the remainder. As the integrating framework for the standards we developed a coherent taxonomy encompassing all elements of a trial's stages. Findings Review of the 144 documents yielded nearly 15 000 discrete standards. After duplicates were removed, 5903 substantive standards remained, distributed in the taxonomy as follows: initiation, 1401 standards, 8 divisions; design, 1869 standards, 16 divisions; conduct, 1473 standards, 8 divisions; analysing and reporting results, 997 standards, four divisions; and post-trial standards, 168 standards, 5 divisions. Conclusions The overwhelming number of source documents and standards uncovered in this study was not anticipated beforehand and confirms the extraordinary complexity of the clinical trials enterprise. This taxonomy of multinational ethical and methodological standards may help trialists and overseers improve the quality of clinical trials, particularly given the globalisation of clinical research. (shrink)

The UK Human Fertilisation and Embryology Authority was right to permit tissue typing preimplantation genetic diagnosisOn July 21 2004, the Human Fertilisation and Embryology Authority , Britain’s regulatory agency for reproductive technologies, revised its policy on preimplantation genetic diagnosis for tissue typing.1,2 The authority of the HFEA to enact such a policy was affirmed by the UK’s highest court, the House of Lords, on April 28 2005.3 Preimplantation genetic diagnosis combines in vitro fertilisation with genetic testing. In PGD, embryos generally (...) undergo biopsy prior to the eight cell stage, followed by genetic testing for a particular trait. Tissue typing PGD is done to identify an embryo that is tissue matched for a child suffering from a severe disease requiring bone marrow or cord blood stem cell transplantation and for whom no living donor exists. This procedure was first performed in 2000.4 Precise matching of tissue types is critical to successful tissue transplant, and the donors of such tissues are often referred to as “saviour siblings”.Where a tissue matched individual already exists, extracting bone marrow from that individual or collecting cord blood already in storage, rather than creating a match, presents the most immediate treatment alternative. Bone marrow donation from adults or other medically competent individuals is not generally ethically contested, and bone marrow donation from medically incompetent individuals is also permissible under certain conditions.5 Where no living tissue donor exists, however, intentionally creating a donor through tissue typing PGD is among a short list of possible treatment options.The July HFEA policy change makes PGD licensable in cases where tissue typing is the only purpose of testing. Previously, PGD was licensable in the UK only for disease testing, and tissue typing PGD was permissible only when …. (shrink)

In this study, we investigated whether differences in the experience of regret may be a potential explanation for damaging behaviours associated with psychopathy and criminal offending. Participants were incarcerated offenders (n = 60) and non-incarcerated controls (n = 20). Psychopathic traits were characterised with the Psychopathic Checklist: Screening Version. Regret was assessed by responses to outcomes on a simulated gambling task. Incarcerated offenders experienced a reduced sense of regret as compared to non-incarcerated controls. We obtained some evidence that specific psychopathic (...) factors and facets could differentially relate to the experience and use of emotions. Our data provide initial evidence of important associations between negative emotions and decision behaviour in the context of criminal offending. (shrink)

We have lost one of the giants of the twentieth century physics when Yoichiro Nambu passed away in July, 2015, at the age of 94. Today's Standard Model, though still incomplete in many respects, is the culmination of the most successful theory of the Universe to date, and it is built upon foundations provided by discoveries made by Nambu in the 1960s: the mechanism of spontaneously broken symmetry in Nature (with G Jona-Lasinio) and the hidden new SU(3) symmetry of quarks (...) and gluons (with M-Y Han). In this volume honoring Nambu's memory, World Scientific Publishing presents a unique collection of papers written by his former colleagues, collaborating researchers and former students and associates, not only citing Nambu's great contributions in physics but also many personal and private reminiscences, some never told before. This book is a volume for all who benefited not only from Nambu's contributions toward understanding the Universe but also his warm and kind persona. It is a great addition to the history of contemporary physics. (shrink)

What makes teaching a moral endeavor? How can we prepare classroom practitioners for engaging in that moral endeavor in meaningful and effective ways? This volume brings together leading scholars who draw upon both their academic expertise and substantial wisdom of practice to offer a variety of perspectives on the challenge of preparing today’s teachers for the moral work of teaching. Book Features: Examines the role that teacher preparation and development can play in addressing the moral work of teaching. Highlights the (...) work of leading scholars from educational psychology, educational philosophy, and teacher education. Provides compelling insights for identifying the next generation of our nation’s best teachers. Contributors: Wolfgang Althof, Karen Benson, Marvin Berkowitz, Donald Blumenfeld-Jones, Elizabeth Campbell, Julie Canniff, Mary Crawford, Lana Daly, Rebecca Evers, Catherine Fallona, Gary Fenstermacher, Anthony Holter, Lisa Johnson, Daniel Lapsley, Darcia Narvaez, Virginia Navarro, Larry Nucci, Joy Pelton, Virginia Richardson, Don Senneville, David Light Shields, Barbara Stengel, Jonatha Vare, Marilyn Watson. (shrink)

More than 200 million children under the age of 5 years are affected by malnutrition worldwide according to the World Health Organization. The Barbados Nutrition Study (BNS) is a 55-year longitudinal study on a Barbadian cohort with histories of moderate to severe protein-energy malnutrition (PEM) limited to the first year of life and a healthy comparison group. Using quantitative electroencephalography (EEG), differences in brain function duringchildhood(lower alpha1 activity and higher theta, alpha2 and beta activity) have previously been highlighted between participants (...) who suffered from early PEM and controls. In order to determine whether similar differences persisted intoadulthood, our current study used recordings obtained during a Go-No-Go task in a subsample of the original BNS cohort [population size (N) = 53] at ages 45–51 years. We found that previously malnourished adults [sample size (n) = 24] had a higher rate of omission errors on the task relative to controls (n= 29). Evoked-Related Potentials (ERP) were significantly different in participants with histories of early PEM, who presented with lower N2 amplitudes. These findings are typically associated with impaired conflict monitoring and/or attention deficits and may therefore be linked to the attentional and executive function deficits that have been previously reported in this cohort in childhood and again in middle adulthood. (shrink)

Cognitive Science, Volume 46, Issue 7, July 2022.

Abstract Context: Established in 1997, Summa Health System’s Medical Ethics Committee (EC) serves as an educational, supportive, and consultative resource to patients/families and providers, and serves to analyze, clarify, and ameliorate dilemmas in clinical care. In 2009 the EC conducted its 100th consult. In 2002 a Palliative Care Consult Service (PCCS) was established to provide supportive services for patients/families facing advanced illness; enhance clinical decision-making during crisis; and improve pain/symptom management. How these services affect one another has thus far been (...) unclear. Objectives: This study describes EC consults: types, reasons, recommendations and utilization, and investigates the impact the PCCS may have on EC consult requests or recommendations. Methods: Retrospective reviews of 100 EC records explored trends and changes in types of consults, reasons for consults, and EC recommendations and utilization. Results: There were 50 EC consults each in the 6 years pre- and post-PCCS. Differences found include: (1) a decrease in number of reasons for consult requests (133–62); (2) changes in top two reasons for EC consult requests from ‘Family opposed to withdrawing life-sustaining treatment (LST)’ and ‘Patient capacity in question’ to ‘Futility’ and ‘Physician opposed to providing LST’; (3) changes in top two recommendations given by the EC from ‘Emotional Support for Patient/Family’ and ‘Initiate DNR Order’ to ‘Comfort Care’ and ‘Withdraw Treatment.’ Overall, 88% of recommendations were followed. Conclusion: PCCS availability and growth throughout the hospital may have influenced EC consult requests. EC consults regarding family opposition to withdrawing LST and EC recommendations for patient/family support declined. Content Type Journal Article Pages 1-16 DOI 10.1007/s10730-011-9170-9 Authors Jessica Richmond Moeller, Department of Psychiatry and Behavioral Sciences, Akron General Medical Center, 400 Wabash Ave, Akron, OH 44307, USA Teresa H. Albanese, Health Services Research and Education Institute, Summa Health System and Northeast Ohio Medical University, 55 Arch St., Suite 1A, Akron, OH 44304, USA Kimberly Garchar, Kent State University, 6000 Frank Ave., N.W, North Canton, OH 44720, USA Julie M. Aultman, Department of Family and Community Medicine, Northeast Ohio Medical University, P.O. Box 95, Rootstown, OH 44272, USA Steven Radwany, Palliative Care and Hospice Services, Summa Health System and Northeast Ohio Medical University, 55 Arch St., Suite 1A, Akron, OH 44304, USA Dean Frate, Internal Medicine, Palliative Care and Hospice Services, Summa Health System and Northeast Ohio Medical University, 55 Arch St., Suite 1A, Akron, OH 44304, USA Journal HEC Forum Online ISSN 1572-8498 Print ISSN 0956-2737. (shrink)